In the present study, in vitro anti- leishmanial activity of Ethyl acetate, Methanolic, Benzene and Chloroform extracts of Nyctanthes arbortristis have been evaluated. Among those extracts Methanolic extracts of Nyctanthes arbortristis shows effective antileishmanial activity against promastigote form of Leishmania donovani. Nycanthic acid,3-4,secotriterpene acid present in Nyctanthes arbortristis may be responsible for inhibiting the growth of parasite. It was found that LC50=150 pg/ml i.e. 50% inhibition at 100 pg/ml and LC90=200 pg/ml for complete inhibition is required to inhibit the growth of Leishmania donovani. The details have been discussed in the paper.
Thyroid disorder are prevalent in Gaya district in the state of Bihar. Thyroid hormones have been shown to influence the haematopoiesis, but the effects of disorders on thyroid hormones and hematological indices levels have not been assessed. The aim of this study was to evaluate some hematological parameters in peripheral blood of hypo- or hyperthyroid patients. Patients treated for thyroid disorders between June 2012 to November 2015 were included. This study evaluated Thyroid stimulating hormone (TSH), thyroxin (T4), and triiodothyronine (T3), blood levels, red blood cell count (RBC), the levels of RBCrelated indices such as Haemoglobin, Granulocytes, Lymphocytes, Monocytes, Eosinophils, Platelet count and also some immunological factors such as the counts of circulating White blood cells (WBC)etc. The details have been discussed in the paper.