The effect of two agrochemicals namely-ammonium sulphate and urea on changes in total oxygen consumption has been studied in a fresh water teleostean fish, Channa punctatus (Bloch). Total oxygen consumption in this fish was 86.54 + 1.4 cc/kg/h. Treatment of sublethal concentration of both urea & ammonium sulphate for 96hrs exposure caused significant decrease in oxygen consumption as compared to control. The effect was more pronounced in ammonium sulphate as compared to urea exposure. The reason for such changes has been discussed in this paper.